In Nigeria, TB laboratory diagnostics faced numerous challenges, including inadequate infrastructure, equipment shortages, and long downtimes for crucial diagnostic tools like GeneXpert machines. These issues hindered the effectiveness of TB management and slowed the country’s progress in combating the disease. The need for more efficient and effective laboratory diagnostics was critical to improving TB detection and treatment outcomes.
With support from USAID, the LEAP Local program, led by Genesis Analytics, embedded a Technical Advisor (TA) focusing on TB Lab Diagnostics within the National TB and Leprosy Control Program (NTBLCP). The TA enhanced laboratory processes and TB diagnostics infrastructure by providing strategic oversight and hands-on support. Key contributions included reviewing national laboratory biosafety guidelines, developing a national tracking tool for GeneXpert module replacement, conducting a pilot study on stool-based testing using the Truenat platform, and developing protocols for the Drug-Resistant Survey (DRS). The TA also created a national guideline and implementation plan for using the COBAS platform for TB diagnosis, monitored 512 GeneXpert machines, and supported NTBLCP’s operational plans and TB initiatives.
These concerted efforts led to significant improvements. The GeneXpert module replacement tracker reduced equipment downtime from 14-60 days to just 3-7 days. The pilot study on stool-based testing provided valuable data on TB detection. The implementation of the national laboratory biosafety guidelines and the operational plan for the COBAS platform improved laboratory safety and diagnostic efficiency. The NTBLCP achieved a major milestone with the approval and dissemination of the National TB Laboratory Operational Plan 2024-2026, ensuring a structured approach to enhancing TB diagnostics across Nigeria.
The LEAP Local initiative, through the dedicated efforts of the Technical Advisor, has significantly strengthened the TB diagnostic network in Nigeria. By focusing on improving laboratory processes and effectively utilizing resources, the initiative has addressed immediate operational challenges and set the stage for long-term advancements in TB diagnostics. This comprehensive approach ensures that Nigeria is well-prepared to tackle future TB challenges with robust and efficient diagnostic infrastructure.